Wellbutrin-SR Wellbutrin-XL
Bupropion
(Wellbutrin SR, Wellbutrin XL) is used to treat depression. Wellbutrin XL
150mg 300mg and Wellbutrin SR 150m 200mg work by inhibiting the reuptake
of dopamine, serotonin, and norepinephrine; an action that results in more
dopamine, serotonin, and norepinephrine to transmit messages to other nerves.
Wellbutrin is unique and unlike other antidepressants in that its major effect
is on dopamine, an effect that is not shared by the selective serotonin reuptake
inhibitors or SSRIs.
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Important Warning about Antidepressant Use from the FDA
Wellbutrin SR - XL Uses
Wellbutrin SR and Wellbutrin XL are used to treat depression. Wellbutrin is also used to treat seasonal affective disorder (SAD; episodes of depression that occur in the fall and winter each year). Bupropion (Zyban) is used to help people stop smoking. Wellbutrin is also sometimes used to treat episodes of depression in patients with bipolar disorder (manic depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods) and to treat attention deficit disorder (ADHD; more difficulty focusing, controlling actions, and remaining still or quiet than other people who are the same age). Talk to your doctor about the possible risks of using this medication for your condition.
Wellbutrin Directions
The extended-release tablet (Wellbutrin XL) is usually taken once daily in the morning. The sustained-release tablet (Wellbutrin SR) is usually taken twice a day, with doses at least 8 hours apart. Wellbutrin may be taken with food if stomach upset occurs.
Wellbutrin Precautions
Before taking Wellbutrin (bupropion), tell your doctor if you have: history of seizures or head injury or brain tumor, heart disease, liver or kidney disease, eating disorder, diabetes, alcohol dependence, any allergies, the intent to quit smoking. Because of the possibility Wellbutrin will make you dizzy and affect coordination, do not drive or operate machinery until you get used to the drug's effects. Limit or avoid consumption of alcoholic beverages; alcohol can increase your risk of seizures. Chronic alcohol users who suddenly stop the intake of alcohol while taking Wellbutrin (bupropion) may increase the risk of having seizures. Suddenly stopping certain tranquilizers (e.g., diazepam, chlordiazepoxide) is not recommended because doing so may increase the risk of having seizures. Elderly patients may be more sensitive to the effects of Wellbutrin. Tell your doctor if you are pregnant or plan to become pregnant before taking Wellbutrin. Wellbutrin passes into breast milk. Because of the potential risk to the infant, breast-feeding while using Wellbutrin is not recommended. Consult your doctor before breast-feeding.
Wellbutrin Side Effects
Wellbutrin is generally well tolerated. Dry mouth, headache, increased sweating, nausea/vomiting, constipation, anxiety, fatigue and blurred vision may occur. If these effects persist or worsen, notify your doctor. Report promptly: unusual weight loss or gain, palpitations, agitation, trouble sleeping. Unlikely but report promptly: tremor, dizziness, fainting, mood changes, slowed movements, difficulty urinating, decreased sex drive, drowsiness. Very unlikely but report promptly: seizures, mental problems, fever, muscle aches, yellowing of the eyes or skin. In the unlikely event you have an allergic reaction to Wellbutrin, seek medical attention immediately. Symptoms may include trouble breathing, rash, itching, swelling, or severe dizziness. If you notice other effects not listed above, contact your doctor or pharmacist.
Wellbutrin Drug Interactions
Before taking Wellbutrin (bupropion) tell your doctor of all nonprescription and prescription medications you may use especially: MAO inhibitors (e.g., isocarboxazid, phenelzine, tranylcypromine, pargyline, selegiline, linezolid, furazolidone), levodopa, ritonavir, corticosteroids (e.g. prednisone), sedatives, adrenaline-like stimulants (e.g., ephedrine), products containing nicotine (e.g., patches or gum). Also report use of drugs which might increase seizure risk (decrease seizure threshold) such as: phenothiazines (e.g., chlorpromazine), tricyclic antidepressants (e.g., amitriptyline), isoniazid (INH), theophylline. Excess caffeine intake can increase the chance of seizures with this drug. Check all nonprescription/prescription drug labels for caffeine. Consult your doctor or pharmacist. A certain product used to help quit smoking contains Wellbutrin (bupropion). Do not take that product while using Wellbutrin. Do not start or stop any medicine without doctor or pharmacist approval.
Wellbutrin Overdose
If overdose of Wellbutrin is suspected, contact your local poison control center or emergency room immediately. Symptoms of Wellbutrin overdose may include seizures, hallucinations, rapid heart rate, and loss of consciousness.
Missed Dose of Wellbutrin
Take any missed dose of Wellbutrin as soon as possible but not if it is within 4 hours of the next dose. If it is time for the next dose, skip the missed dose and resume your regular schedule. Do not "double-up" the dose of Wellbutrin.
Medical Disclaimer: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. This antidepressant information should not be construed so as to indicate that use of this antidepressant or anti-anxiety medication is safe, appropriate, or effective for you. Please consult your healthcare professional before using this or any other prescription or non-prescription antidepressant medication.
